FBXW7 - PIF1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)
PIF1	ENSG00000140451	No diseases in record	No drugs in record	magnesium ion binding ATP binding telomerase inhibitor activity single-stranded DNA-dependent ATP-dependent DNA helicase activity ATP-dependent 5'-3' DNA/RNA helicase activity telomeric DNA binding ATP-dependent 5'-3' DNA helicase activity G-quadruplex DNA binding hydrolase activity nucleotide binding helicase activity single-stranded DNA binding DNA helicase activity DNA binding	PIF1 (S. cerevisiae) RRM3 (S. cerevisiae)