FBXW7 - PPM1D

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)
PPM1D	ENSG00000170836	glioma ovarian cancer breast cancer	No drugs in record	protein serine/threonine phosphatase activity protein binding metal ion binding mitogen-activated protein kinase binding	PTC2 (S. cerevisiae) PTC3 (S. cerevisiae)