FBXW7 - CHEK2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)
CHEK2	ENSG00000183765	breast	No drugs in record	protein serine/threonine kinase activity protein binding ATP binding protein kinase binding ubiquitin protein ligase binding identical protein binding protein homodimerization activity metal ion binding	RAD53 (S. cerevisiae) chk-2 (C. elegans) T08D2.7 (C. elegans) lok (D. melanogaster)