FBXW7 - CDK9

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)
CDK9	ENSG00000136807	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding transcription coactivator binding DNA binding chromatin binding protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity kinase activity 7SK snRNA binding transcription factor binding cyclin binding transcription regulatory region DNA binding cyclin-dependent protein kinase activity	CTK1 (S. cerevisiae) cdk-9 (C. elegans) Cdk9 (D. melanogaster)