PPP1CA - POLE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPP1CA	ENSG00000172531	No diseases in record	No drugs in record	phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein binding protein phosphatase 1 binding phosphatase activity protein complex binding ribonucleoprotein complex binding metal ion binding	GLC7 (S. cerevisiae) Pp1-87B (D. melanogaster) flw (D. melanogaster) Pp1-13C (D. melanogaster) Pp1alpha-96A (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)