ARFGEF1 - CBL

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ARFGEF1	ENSG00000066777	No diseases in record	No drugs in record	guanyl-nucleotide exchange factor activity ARF guanyl-nucleotide exchange factor activity protein binding myosin binding protein kinase A regulatory subunit binding GTPase activator activity	SEC7 (S. cerevisiae) Sec71 (D. melanogaster)
CBL	ENSG00000110395	AML JMML MDS	No drugs in record	phosphotyrosine residue binding transcription factor activity, sequence-specific DNA binding ubiquitin-protein transferase activity signal transducer activity calcium ion binding protein binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding phosphatidylinositol 3-kinase regulatory subunit binding ephrin receptor binding ubiquitin protein ligase activity cadherin binding involved in cell-cell adhesion	sli-1 (C. elegans) Cbl (D. melanogaster)