KDM4A - EP300

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDM4A	ENSG00000066135	No diseases in record	No drugs in record	double-stranded DNA binding protein binding zinc ion binding ubiquitin protein ligase binding histone demethylase activity methylated histone binding histone demethylase activity (H3-K36 specific) histone demethylase activity (H3-K9 specific)	GIS1 (S. cerevisiae) RPH1 (S. cerevisiae) jmjd-2 (C. elegans)
EP300	ENSG00000100393	colorectal breast pancreatic AML ALL DLBCL	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding core promoter binding RNA polymerase II activating transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding p53 binding DNA binding chromatin binding damaged DNA binding transcription coactivator activity histone acetyltransferase activity lysine N-acetyltransferase activity, acting on acetyl phosphate as donor protein binding beta-catenin binding protein C-terminus binding transcription factor binding zinc ion binding acetyltransferase activity transferase activity, transferring acyl groups chromatin DNA binding activating transcription factor binding peptide N-acetyltransferase activity nuclear hormone receptor binding androgen receptor binding pre-mRNA intronic binding	BDF1 (S. cerevisiae) BDF2 (S. cerevisiae) nej (D. melanogaster)