VAV1 - ARHGEF12

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
VAV1	ENSG00000141968	T-cell lymphoma	No drugs in record	transcription factor activity, sequence-specific DNA binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity protein binding Rac guanyl-nucleotide exchange factor activity metal ion binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	CDC24 (S. cerevisiae)
ARHGEF12	ENSG00000196914	AML	No drugs in record	G-protein coupled receptor binding guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity protein binding	ROM1 (S. cerevisiae) ROM2 (S. cerevisiae) RhoGEF2 (D. melanogaster)