BRCA1 - HMGB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
BRCA1	ENSG00000012048	ovarian breast	No drugs in record	DNA binding damaged DNA binding transcription coactivator activity RNA binding ubiquitin-protein transferase activity protein binding zinc ion binding tubulin binding enzyme binding ubiquitin protein ligase binding transcription regulatory region DNA binding androgen receptor binding	No GO terms in record
HMGB1	ENSG00000189403	No diseases in record	No drugs in record	four-way junction DNA binding bubble DNA binding lipopolysaccharide binding phosphatidylserine binding damaged DNA binding double-stranded DNA binding single-stranded DNA binding transcription factor activity, sequence-specific DNA binding double-stranded RNA binding single-stranded RNA binding cytokine activity protein binding transcription factor binding DNA binding, bending calcium-dependent protein kinase regulator activity lyase activity C-X-C chemokine binding protein kinase activator activity chemoattractant activity RAGE receptor binding DNA polymerase binding repressing transcription factor binding supercoiled DNA binding	NHP6A (S. cerevisiae) NHP6B (S. cerevisiae) hmg-1.2 (C. elegans)