TOP2B - EIF4G1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
EIF4G1	ENSG00000114867	No diseases in record	No drugs in record	translation initiation factor activity protein binding translation factor activity, RNA binding eukaryotic initiation factor 4E binding cadherin binding involved in cell-cell adhesion	TIF4631 (S. cerevisiae) TIF4632 (S. cerevisiae) ifg-1 (C. elegans) eIF4G2 (D. melanogaster)