ABL1 - BLM

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
BLM	ENSG00000197299	leukaemia lymphoma skin squamous cell other tumour types	No drugs in record	bubble DNA binding p53 binding single-stranded DNA binding ATP-dependent DNA helicase activity helicase activity protein binding ATP binding ATP-dependent helicase activity four-way junction helicase activity ATPase activity annealing helicase activity ATP-dependent 3'-5' DNA helicase activity G-quadruplex DNA binding DNA helicase activity DNA-dependent ATPase activity Y-form DNA binding	SGS1 (S. cerevisiae) him-6 (C. elegans) Blm (D. melanogaster)