WT1 - BLM

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
WT1 ENSG00000184937 Wilms tumour
desmoplastic small round cell tumour

No drugs in record

transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
RNA binding
protein binding
zinc ion binding
double-stranded methylated DNA binding
sequence-specific DNA binding
transcription regulatory region DNA binding
hemi-methylated DNA-binding
C2H2 zinc finger domain binding
MIG1 (S. cerevisiae)
MIG2 (S. cerevisiae)
MIG3 (S. cerevisiae)
BLM ENSG00000197299 leukaemia
lymphoma
skin squamous cell
other tumour types

No drugs in record

bubble DNA binding
p53 binding
single-stranded DNA binding
ATP-dependent DNA helicase activity
helicase activity
protein binding
ATP binding
ATP-dependent helicase activity
four-way junction helicase activity
ATPase activity
annealing helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
DNA helicase activity
DNA-dependent ATPase activity
Y-form DNA binding
SGS1 (S. cerevisiae)
him-6 (C. elegans)
Blm (D. melanogaster)