ATR - POLE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ATR	ENSG00000175054	endometrial gastric epithelial ovarian myeloma oropharyngeal	No drugs in record	DNA binding protein kinase activity protein serine/threonine kinase activity protein binding ATP binding MutLalpha complex binding MutSalpha complex binding	MEC1 (S. cerevisiae) atl-1 (C. elegans) mei-41 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)