PABPC1 - ERBB2

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
PABPC1 ENSG00000070756 HNSCC
biliary tract carcinoma

No drugs in record

nucleotide binding
mRNA 3'-UTR binding
protein binding
protein C-terminus binding
poly(A) binding
poly(U) RNA binding
translation activator activity
PAB1 (S. cerevisiae)
ERBB2 ENSG00000141736 breast
ovarian
other tumour types
NSCLC
gastric
AFATINIB
LAPATINIB
PERTUZUMAB
TRASTUZUMAB
TRASTUZUMAB EMTANSINE
VANDETANIB
RNA polymerase I core binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
protein C-terminus binding
protein phosphatase binding
identical protein binding
ErbB-3 class receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
protein dimerization activity
growth factor binding
let-23 (C. elegans)
Egfr (D. melanogaster)