JAK1 - MAPKAPK2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
JAK1	ENSG00000162434	ALL	RUXOLITINIB TOFACITINIB	protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity receptor binding growth hormone receptor binding protein binding ATP binding protein phosphatase binding ubiquitin protein ligase binding CCR5 chemokine receptor binding metal ion binding	hop (D. melanogaster)
MAPKAPK2	ENSG00000162889	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity calmodulin-dependent protein kinase activity signal transducer activity protein binding calmodulin binding ATP binding calcium-dependent protein serine/threonine kinase activity	RCK1 (S. cerevisiae) RCK2 (S. cerevisiae) MAPk-Ak2 (D. melanogaster)