TDP1 - ABL1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TDP1	ENSG00000042088	No diseases in record	No drugs in record	double-stranded DNA binding single-stranded DNA binding exonuclease activity protein binding 3'-tyrosyl-DNA phosphodiesterase activity hydrolase activity nuclease activity 5'-tyrosyl-DNA phosphodiesterase activity phosphoric diester hydrolase activity	TDP1 (S. cerevisiae) gkt (D. melanogaster)
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)