CUL3 - KDM5A

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CUL3	ENSG00000036257	lung cancer	No drugs in record	protein binding cyclin binding POZ domain binding ubiquitin protein ligase binding protein homodimerization activity protein heterodimerization activity ubiquitin-protein transferase activity ubiquitin protein ligase activity	CDC53 (S. cerevisiae) Cul3 (D. melanogaster)
KDM5A	ENSG00000073614	AML	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding zinc ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors chromatin DNA binding histone demethylase activity	JHD2 (S. cerevisiae) rbr-2 (C. elegans)