POLR3A - NSD1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
POLR3A	ENSG00000148606	No diseases in record	No drugs in record	DNA binding chromatin binding DNA-directed 5'-3' RNA polymerase activity metal ion binding RNA polymerase III activity	RPO31 (S. cerevisiae) rpc-1 (C. elegans) CG17209 (D. melanogaster)
NSD1	ENSG00000165671	AML	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding chromatin binding transcription cofactor activity transcription corepressor activity zinc ion binding histone-lysine N-methyltransferase activity estrogen receptor binding histone methyltransferase activity (H4-K20 specific) retinoic acid receptor binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	SET2 (S. cerevisiae)