CHD4 - RB1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CHD4	ENSG00000111642	uterine serous carcinoma	No drugs in record	RNA polymerase II repressing transcription factor binding DNA binding ATP-dependent DNA helicase activity histone deacetylase activity protein binding ATP binding microtubule binding zinc ion binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	CHD1 (S. cerevisiae) let-418 (C. elegans) chd-3 (C. elegans)
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)