CREBBP - CHD4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CREBBP	ENSG00000005339	ALL AML DLBCL B-NHL	No drugs in record	core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II transcription factor binding RNA polymerase II activating transcription factor binding RNA polymerase II transcription coactivator activity transcriptional repressor activity, RNA polymerase II transcription factor binding p53 binding chromatin binding damaged DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity histone acetyltransferase activity signal transducer activity protein binding transcription factor binding zinc ion binding acetyltransferase activity peptide N-acetyltransferase activity MRF binding	BDF1 (S. cerevisiae) BDF2 (S. cerevisiae) nej (D. melanogaster)
CHD4	ENSG00000111642	uterine serous carcinoma	No drugs in record	RNA polymerase II repressing transcription factor binding DNA binding ATP-dependent DNA helicase activity histone deacetylase activity protein binding ATP binding microtubule binding zinc ion binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding nucleosomal DNA binding	CHD1 (S. cerevisiae) let-418 (C. elegans) chd-3 (C. elegans)