H3F3A - NSD1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
H3F3A	ENSG00000163041	glioma	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding protein binding nucleosomal DNA binding histone binding protein heterodimerization activity	HHT1 (S. cerevisiae) HHT2 (S. cerevisiae)
NSD1	ENSG00000165671	AML	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding chromatin binding transcription cofactor activity transcription corepressor activity zinc ion binding histone-lysine N-methyltransferase activity estrogen receptor binding histone methyltransferase activity (H4-K20 specific) retinoic acid receptor binding retinoid X receptor binding thyroid hormone receptor binding histone methyltransferase activity (H3-K36 specific) androgen receptor binding	SET2 (S. cerevisiae)