EP300 - TAF1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EP300	ENSG00000100393	colorectal breast pancreatic AML ALL DLBCL	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding core promoter binding RNA polymerase II activating transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding p53 binding DNA binding chromatin binding damaged DNA binding transcription coactivator activity histone acetyltransferase activity lysine N-acetyltransferase activity, acting on acetyl phosphate as donor protein binding beta-catenin binding protein C-terminus binding transcription factor binding zinc ion binding acetyltransferase activity transferase activity, transferring acyl groups chromatin DNA binding activating transcription factor binding peptide N-acetyltransferase activity nuclear hormone receptor binding androgen receptor binding pre-mRNA intronic binding	BDF1 (S. cerevisiae) BDF2 (S. cerevisiae) nej (D. melanogaster)
TAF1	ENSG00000147133	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly p53 binding transcription coactivator activity histone acetyltransferase activity protein serine/threonine kinase activity protein binding ATP binding transcription factor binding kinase activity TBP-class protein binding sequence-specific DNA binding protein heterodimerization activity ubiquitin conjugating enzyme activity lysine-acetylated histone binding acetyl-CoA binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly transcription regulatory region DNA binding transferase activity chromatin binding protein complex scaffold activity transferase activity, transferring acyl groups H4 histone acetyltransferase activity histone acetyltransferase activity (H3-K14 specific)	TAF1 (S. cerevisiae) taf-1 (C. elegans) Taf1 (D. melanogaster)