DROSHA - TAF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DROSHA	ENSG00000113360	Wilms tumour NSCLC bladder carcinoma	No drugs in record	lipopolysaccharide binding double-stranded RNA binding ribonuclease III activity protein binding protein homodimerization activity metal ion binding primary miRNA binding RNA binding	drsh-1 (C. elegans) drosha (D. melanogaster)
TAF1	ENSG00000147133	No diseases in record	No drugs in record	RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly p53 binding transcription coactivator activity histone acetyltransferase activity protein serine/threonine kinase activity protein binding ATP binding transcription factor binding kinase activity TBP-class protein binding sequence-specific DNA binding protein heterodimerization activity ubiquitin conjugating enzyme activity lysine-acetylated histone binding acetyl-CoA binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly transcription regulatory region DNA binding transferase activity chromatin binding protein complex scaffold activity transferase activity, transferring acyl groups H4 histone acetyltransferase activity histone acetyltransferase activity (H3-K14 specific)	TAF1 (S. cerevisiae) taf-1 (C. elegans) Taf1 (D. melanogaster)