ABL1 - MUS81

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABL1	ENSG00000097007	CML ALL T-ALL	BOSUTINIB DASATINIB IMATINIB NILOTINIB PONATINIB REGORAFENIB	magnesium ion binding DNA binding actin monomer binding nicotinate-nucleotide adenylyltransferase activity protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein kinase C binding protein binding ATP binding protein C-terminus binding SH3 domain binding syntaxin binding manganese ion binding actin filament binding mitogen-activated protein kinase binding proline-rich region binding receptor binding	abl-1 (C. elegans) Abl (D. melanogaster)
MUS81	ENSG00000172732	No diseases in record	No drugs in record	DNA binding endodeoxyribonuclease activity protein binding metal ion binding 3'-flap endonuclease activity crossover junction endodeoxyribonuclease activity nuclease activity endonuclease activity enzyme inhibitor activity hydrolase activity	MUS81 (S. cerevisiae) mus81 (D. melanogaster)