MRE11 - NRG1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
MRE11 ENSG00000020922

No diseases in record

No drugs in record

hydrolase activity
exonuclease activity
endonuclease activity
protein complex scaffold activity
manganese ion binding
nuclease activity
3'-5' exonuclease activity
G-quadruplex DNA binding
single-stranded telomeric DNA binding
double-stranded telomeric DNA binding
telomeric DNA binding
endodeoxyribonuclease activity
adenylate kinase activity
protein binding
DNA end binding
single-stranded DNA endodeoxyribonuclease activity
Y-form DNA binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
double-stranded DNA 3'-5' exodeoxyribonuclease activity
MRE11 (S. cerevisiae)
mre-11 (C. elegans)
NRG1 ENSG00000157168 NSCLC

No drugs in record

transcription cofactor activity
protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
cytokine activity
ErbB-2 class receptor binding
integrin binding
growth factor activity
transmembrane receptor protein tyrosine kinase activator activity
receptor tyrosine kinase binding
ErbB-3 class receptor binding
chemorepellent activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription factor binding
DNA binding
sequence-specific DNA binding
metal ion binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II repressing transcription factor binding
nucleic acid binding

No GO terms in record