MRE11 - KALRN

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MRE11	ENSG00000020922	No diseases in record	No drugs in record	hydrolase activity exonuclease activity endonuclease activity protein complex scaffold activity manganese ion binding nuclease activity 3'-5' exonuclease activity G-quadruplex DNA binding single-stranded telomeric DNA binding double-stranded telomeric DNA binding telomeric DNA binding endodeoxyribonuclease activity adenylate kinase activity protein binding DNA end binding single-stranded DNA endodeoxyribonuclease activity Y-form DNA binding single-stranded DNA 3'-5' exodeoxyribonuclease activity double-stranded DNA 3'-5' exodeoxyribonuclease activity	MRE11 (S. cerevisiae) mre-11 (C. elegans)
KALRN	ENSG00000160145	No diseases in record	No drugs in record	protein serine/threonine kinase activity guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity GTPase activator activity ATP binding Rac guanyl-nucleotide exchange factor activity metal ion binding	unc-73 (C. elegans) trio (D. melanogaster)