MRE11 - PMS1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MRE11	ENSG00000020922	No diseases in record	No drugs in record	hydrolase activity exonuclease activity endonuclease activity protein complex scaffold activity manganese ion binding nuclease activity 3'-5' exonuclease activity G-quadruplex DNA binding single-stranded telomeric DNA binding double-stranded telomeric DNA binding telomeric DNA binding endodeoxyribonuclease activity adenylate kinase activity protein binding DNA end binding single-stranded DNA endodeoxyribonuclease activity Y-form DNA binding single-stranded DNA 3'-5' exodeoxyribonuclease activity double-stranded DNA 3'-5' exodeoxyribonuclease activity	MRE11 (S. cerevisiae) mre-11 (C. elegans)
PMS1	ENSG00000064933	colorectal endometrial ovarian	No drugs in record	DNA binding single-stranded DNA binding ATP binding ATPase activity mismatched DNA binding heteroduplex DNA loop binding DNA insertion or deletion binding dinucleotide insertion or deletion binding double-stranded DNA binding	PMS1 (S. cerevisiae) pms-2 (C. elegans)