CHEK1 - NRG1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CHEK1	ENSG00000149554	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein binding ATP binding kinase activity histone kinase activity (H3-T11 specific)	CHK1 (S. cerevisiae) grp (D. melanogaster)
NRG1	ENSG00000157168	NSCLC	No drugs in record	transcription cofactor activity protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity cytokine activity ErbB-2 class receptor binding integrin binding growth factor activity transmembrane receptor protein tyrosine kinase activator activity receptor tyrosine kinase binding ErbB-3 class receptor binding chemorepellent activity phosphatidylinositol-4,5-bisphosphate 3-kinase activity RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription factor binding DNA binding sequence-specific DNA binding metal ion binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II repressing transcription factor binding nucleic acid binding	No GO terms in record