RB1 - PIF1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RB1	ENSG00000139687	retinoblastoma sarcoma breast small cell lung carcinoma	No drugs in record	core promoter binding RNA polymerase II activating transcription factor binding DNA binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity protein binding transcription factor binding kinase binding ubiquitin protein ligase binding identical protein binding androgen receptor binding phosphoprotein binding	lin-35 (C. elegans) Rbf2 (D. melanogaster)
PIF1	ENSG00000140451	No diseases in record	No drugs in record	magnesium ion binding ATP binding telomerase inhibitor activity single-stranded DNA-dependent ATP-dependent DNA helicase activity ATP-dependent 5'-3' DNA/RNA helicase activity telomeric DNA binding ATP-dependent 5'-3' DNA helicase activity G-quadruplex DNA binding hydrolase activity nucleotide binding helicase activity single-stranded DNA binding DNA helicase activity DNA binding	PIF1 (S. cerevisiae) RRM3 (S. cerevisiae)