GLI3 - FBXW7

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GLI3	ENSG00000106571	No diseases in record	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding beta-catenin binding histone acetyltransferase binding histone deacetylase binding metal ion binding	tra-1 (C. elegans) ci (D. melanogaster)
FBXW7	ENSG00000109670	colorectal endometrial T-ALL	No drugs in record	ubiquitin-protein transferase activity protein binding cyclin binding protein binding, bridging ubiquitin protein ligase binding identical protein binding phosphothreonine residue binding ubiquitin-protein transferase activator activity	MET30 (S. cerevisiae) sel-10 (C. elegans) ago (D. melanogaster)