MCM5 - POLE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MCM5	ENSG00000100297	No diseases in record	No drugs in record	DNA helicase activity chromatin binding DNA replication origin binding protein binding ATP binding hydrolase activity DNA binding single-stranded DNA binding helicase activity nucleotide binding single-stranded DNA-dependent ATP-dependent DNA helicase activity 3'-5' DNA helicase activity ATP-dependent DNA helicase activity	MCM5 (S. cerevisiae) mcm-5 (C. elegans) Mcm5 (D. melanogaster)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)