TOP2B - MCM5

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
MCM5	ENSG00000100297	No diseases in record	No drugs in record	DNA helicase activity chromatin binding DNA replication origin binding protein binding ATP binding hydrolase activity DNA binding single-stranded DNA binding helicase activity nucleotide binding single-stranded DNA-dependent ATP-dependent DNA helicase activity 3'-5' DNA helicase activity ATP-dependent DNA helicase activity	MCM5 (S. cerevisiae) mcm-5 (C. elegans) Mcm5 (D. melanogaster)