ETV6 - AKT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ETV6	ENSG00000139083	congenital fibrosarcoma multiple different leukaemia and lymphoma tumour types including ALL secretory breast MDS	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding protein domain specific binding	aop (D. melanogaster)
AKT1	ENSG00000142208	breast colorectal ovarian NSCLC	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein kinase C binding protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding kinase activity enzyme binding nitric-oxide synthase regulator activity GTPase activating protein binding identical protein binding phosphatidylinositol-3,4-bisphosphate binding protein phosphatase 2A binding 14-3-3 protein binding phosphatidylinositol binding	SCH9 (S. cerevisiae) YPK1 (S. cerevisiae) YPK2 (S. cerevisiae) akt-1 (C. elegans) akt-2 (C. elegans) Akt1 (D. melanogaster)