SMAD6 - AKT1

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SMAD6 ENSG00000137834

No diseases in record

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
protein binding
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
ubiquitin protein ligase binding
type I transforming growth factor beta receptor binding
identical protein binding
transcription regulatory region DNA binding
metal ion binding
co-SMAD binding
I-SMAD binding
R-SMAD binding
type I activin receptor binding
daf-14 (C. elegans)
daf-8 (C. elegans)
Dad (D. melanogaster)
AKT1 ENSG00000142208 breast
colorectal
ovarian
NSCLC

No drugs in record

protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein kinase C binding
protein binding
ATP binding
phosphatidylinositol-3,4,5-trisphosphate binding
kinase activity
enzyme binding
nitric-oxide synthase regulator activity
GTPase activating protein binding
identical protein binding
phosphatidylinositol-3,4-bisphosphate binding
protein phosphatase 2A binding
14-3-3 protein binding
phosphatidylinositol binding
SCH9 (S. cerevisiae)
YPK1 (S. cerevisiae)
YPK2 (S. cerevisiae)
akt-1 (C. elegans)
akt-2 (C. elegans)
Akt1 (D. melanogaster)