ACVR1 - AKT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ACVR1	ENSG00000115170	DIPG	No drugs in record	protein kinase activity protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity transforming growth factor beta receptor activity, type I protein binding ATP binding peptide hormone binding protein homodimerization activity SMAD binding metal ion binding activin binding transforming growth factor beta binding activin receptor activity, type I	sax (D. melanogaster)
AKT1	ENSG00000142208	breast colorectal ovarian NSCLC	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein kinase C binding protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding kinase activity enzyme binding nitric-oxide synthase regulator activity GTPase activating protein binding identical protein binding phosphatidylinositol-3,4-bisphosphate binding protein phosphatase 2A binding 14-3-3 protein binding phosphatidylinositol binding	SCH9 (S. cerevisiae) YPK1 (S. cerevisiae) YPK2 (S. cerevisiae) akt-1 (C. elegans) akt-2 (C. elegans) Akt1 (D. melanogaster)