PIKFYVE - AKT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIKFYVE	ENSG00000115020	No diseases in record	No drugs in record	1-phosphatidylinositol-3-phosphate 5-kinase activity protein binding ATP binding zinc ion binding 1-phosphatidylinositol-4-phosphate 5-kinase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	FAB1 (S. cerevisiae) ppk-3 (C. elegans)
AKT1	ENSG00000142208	breast colorectal ovarian NSCLC	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein kinase C binding protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding kinase activity enzyme binding nitric-oxide synthase regulator activity GTPase activating protein binding identical protein binding phosphatidylinositol-3,4-bisphosphate binding protein phosphatase 2A binding 14-3-3 protein binding phosphatidylinositol binding	SCH9 (S. cerevisiae) YPK1 (S. cerevisiae) YPK2 (S. cerevisiae) akt-1 (C. elegans) akt-2 (C. elegans) Akt1 (D. melanogaster)