ATM - KDM6A

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
ATM ENSG00000149311 T-PLL
leukaemia
lymphoma
medulloblastoma
glioma

No drugs in record

DNA binding
protein serine/threonine kinase activity
DNA-dependent protein kinase activity
protein binding
ATP binding
1-phosphatidylinositol-3-kinase activity
protein complex binding
protein dimerization activity
protein N-terminus binding
TEL1 (S. cerevisiae)
tefu (D. melanogaster)
KDM6A ENSG00000147050 renal cell carcinoma
bladder carcinoma
oesophageal SCC
MM
medulloblastoma
T-ALL
other tumour types

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
chromatin DNA binding
histone demethylase activity
identical protein binding
metal ion binding
dioxygenase activity
histone demethylase activity (H3-K27 specific)
CYC8 (S. cerevisiae)
Utx (D. melanogaster)

References