HSPA8 - LEF1

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HSPA8	ENSG00000109971	No diseases in record	No drugs in record	G-protein coupled receptor binding phosphatidylserine binding protein binding ATP binding ATPase activity enzyme binding MHC class II protein complex binding heat shock protein binding ubiquitin protein ligase binding ATPase activity, coupled unfolded protein binding C3HC4-type RING finger domain binding cadherin binding involved in cell-cell adhesion	KAR2 (S. cerevisiae) hsp-1 (C. elegans) Hsc70-4 (D. melanogaster) Hsc70-1 (D. melanogaster)
LEF1	ENSG00000138795	B-ALL T-ALL eyelid sebaceous carcinoma AML lymphomas	No drugs in record	RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding beta-catenin binding transcription factor binding DNA binding, bending estrogen receptor activity estrogen receptor binding enhancer binding histone binding histone deacetylase binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process sequence-specific DNA binding transcription regulatory region DNA binding gamma-catenin binding armadillo repeat domain binding C2H2 zinc finger domain binding	pop-1 (C. elegans) pan (D. melanogaster)