DICER1 - STAT3

H. sapiens

SDL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DICER1	ENSG00000100697	sex cord-stromal tumour TGCT embryonal rhabdomyosarcoma pleuropulmonary blastoma pituitary blastoma Wilms tumour thyroid cancer other tumour types	No drugs in record	double-stranded RNA binding helicase activity endoribonuclease activity ribonuclease III activity deoxyribonuclease I activity protein binding ATP binding protein domain specific binding siRNA binding metal ion binding pre-miRNA binding	MPH1 (S. cerevisiae) dcr-1 (C. elegans) Dcr-1 (D. melanogaster)
STAT3	ENSG00000168610	T-cell large granular lymphocytic leukaemia paediatric large granular lymphocytic leukaemia	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II repressing transcription factor binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding transcription factor activity, sequence-specific DNA binding signal transducer activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding protein binding transcription factor binding protein kinase binding protein phosphatase binding chromatin DNA binding CCR5 chemokine receptor binding glucocorticoid receptor binding identical protein binding transcription regulatory region DNA binding protein dimerization activity	No GO terms in record