DICER1 - SMAD3

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
DICER1 ENSG00000100697 sex cord-stromal tumour
TGCT
embryonal rhabdomyosarcoma
pleuropulmonary blastoma
pituitary blastoma
Wilms tumour
thyroid cancer
other tumour types

No drugs in record

double-stranded RNA binding
helicase activity
endoribonuclease activity
ribonuclease III activity
deoxyribonuclease I activity
protein binding
ATP binding
protein domain specific binding
siRNA binding
metal ion binding
pre-miRNA binding
MPH1 (S. cerevisiae)
dcr-1 (C. elegans)
Dcr-1 (D. melanogaster)
SMAD3 ENSG00000166949 colorectal carcinoma
oral squamous cell carcinoma

No drugs in record

RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription factor activity, RNA polymerase II core promoter sequence-specific
core promoter proximal region sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
transcription factor activity, sequence-specific DNA binding
transforming growth factor beta receptor binding
protein binding
collagen binding
beta-catenin binding
transcription factor binding
zinc ion binding
protein kinase binding
phosphatase binding
transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
chromatin DNA binding
ubiquitin protein ligase binding
enhancer binding
identical protein binding
protein homodimerization activity
ubiquitin binding
bHLH transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
co-SMAD binding
R-SMAD binding
transcription factor activity, protein binding
sma-3 (C. elegans)
sma-2 (C. elegans)