Gene Name
|
Gene ID
|
Diseases
|
Drugs
|
GO terms
|
Orthologs
|
DICER1
|
ENSG00000100697
|
sex cord-stromal tumour
TGCT
embryonal rhabdomyosarcoma
pleuropulmonary blastoma
pituitary blastoma
Wilms tumour
thyroid cancer
other tumour types
|
No drugs in record
|
double-stranded RNA binding
helicase activity
endoribonuclease activity
ribonuclease III activity
deoxyribonuclease I activity
protein binding
ATP binding
protein domain specific binding
siRNA binding
metal ion binding
pre-miRNA binding
|
MPH1 (S. cerevisiae)
dcr-1 (C. elegans)
Dcr-1 (D. melanogaster)
|
LRRK2
|
ENSG00000188906
|
No diseases in record
|
No drugs in record
|
SNARE binding
glycoprotein binding
actin binding
GTPase activity
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase activity
GTPase activator activity
protein binding
ATP binding
GTP binding
microtubule binding
tubulin binding
kinase activity
Rho GTPase binding
syntaxin-1 binding
receptor signaling complex scaffold activity
clathrin binding
GTP-dependent protein kinase activity
peroxidase inhibitor activity
co-receptor binding
identical protein binding
protein homodimerization activity
ion channel binding
protein kinase A binding
beta-catenin destruction complex binding
|
MEK1 (S. cerevisiae)
|