DICER1 - SKP1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DICER1	ENSG00000100697	sex cord-stromal tumour TGCT embryonal rhabdomyosarcoma pleuropulmonary blastoma pituitary blastoma Wilms tumour thyroid cancer other tumour types	No drugs in record	double-stranded RNA binding helicase activity endoribonuclease activity ribonuclease III activity deoxyribonuclease I activity protein binding ATP binding protein domain specific binding siRNA binding metal ion binding pre-miRNA binding	MPH1 (S. cerevisiae) dcr-1 (C. elegans) Dcr-1 (D. melanogaster)
SKP1	ENSG00000113558	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding beta-catenin binding cullin family protein binding ubiquitin protein ligase activity DNA replication origin binding DNA binding	SKP1 (S. cerevisiae) skr-2 (C. elegans) skr-1 (C. elegans) skr-17 (C. elegans) skr-9 (C. elegans) skr-8 (C. elegans) skr-7 (C. elegans) skr-18 (C. elegans) skr-10 (C. elegans) skr-13 (C. elegans) skr-12 (C. elegans) SkpA (D. melanogaster) SkpE (D. melanogaster) SkpB (D. melanogaster) SkpF (D. melanogaster) SkpC (D. melanogaster) SkpD (D. melanogaster)