DICER1 - AKT1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DICER1	ENSG00000100697	sex cord-stromal tumour TGCT embryonal rhabdomyosarcoma pleuropulmonary blastoma pituitary blastoma Wilms tumour thyroid cancer other tumour types	No drugs in record	double-stranded RNA binding helicase activity endoribonuclease activity ribonuclease III activity deoxyribonuclease I activity protein binding ATP binding protein domain specific binding siRNA binding metal ion binding pre-miRNA binding	MPH1 (S. cerevisiae) dcr-1 (C. elegans) Dcr-1 (D. melanogaster)
AKT1	ENSG00000142208	breast colorectal ovarian NSCLC	No drugs in record	protein kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein kinase C binding protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding kinase activity enzyme binding nitric-oxide synthase regulator activity GTPase activating protein binding identical protein binding phosphatidylinositol-3,4-bisphosphate binding protein phosphatase 2A binding 14-3-3 protein binding phosphatidylinositol binding	SCH9 (S. cerevisiae) YPK1 (S. cerevisiae) YPK2 (S. cerevisiae) akt-1 (C. elegans) akt-2 (C. elegans) Akt1 (D. melanogaster)