FOXO1 - SKI

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FOXO1	ENSG00000150907	alveolar rhabdomyosarcoma	No drugs in record	RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription factor binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription coactivator binding chromatin binding protein binding beta-catenin binding ubiquitin protein ligase binding sequence-specific DNA binding protein phosphatase 2A binding	HCM1 (S. cerevisiae) daf-16 (C. elegans) foxo (D. melanogaster)
SKI	ENSG00000157933	melanoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding chromatin binding transcription corepressor activity protein binding zinc ion binding protein kinase binding protein domain specific binding ubiquitin protein ligase binding SMAD binding histone deacetylase inhibitor activity repressing transcription factor binding	Snoo (D. melanogaster)