ITCH - FOXO1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITCH	ENSG00000078747	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding ubiquitin-like protein transferase activity ribonucleoprotein complex binding CXCR chemokine receptor binding ubiquitin protein ligase activity	RSP5 (S. cerevisiae) wwp-1 (C. elegans) Su(dx) (D. melanogaster)
FOXO1	ENSG00000150907	alveolar rhabdomyosarcoma	No drugs in record	RNA polymerase II transcription factor activity, sequence-specific DNA binding transcription factor activity, transcription factor binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription coactivator binding chromatin binding protein binding beta-catenin binding ubiquitin protein ligase binding sequence-specific DNA binding protein phosphatase 2A binding	HCM1 (S. cerevisiae) daf-16 (C. elegans) foxo (D. melanogaster)