PIAS1 - CDK6

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PIAS1	ENSG00000033800	No diseases in record	No drugs in record	DNA binding transcription coactivator activity transcription corepressor activity protein binding protein C-terminus binding transcription factor binding zinc ion binding ligase activity SUMO transferase activity enzyme binding protein domain specific binding ubiquitin protein ligase binding androgen receptor binding SUMO ligase activity	NFI1 (S. cerevisiae) SIZ1 (S. cerevisiae) gei-17 (C. elegans) Su(var)2-10 (D. melanogaster)
CDK6	ENSG00000105810	ALL	PALBOCICLIB	cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding cyclin binding FBXO family protein binding	CDC28 (S. cerevisiae) cdk-4 (C. elegans) Cdk4 (D. melanogaster)