TOP2B - ATRX

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
ATRX	ENSG00000085224	pancreatic neuroendocrine tumours paediatric GBM	No drugs in record	DNA binding DNA helicase activity chromatin binding helicase activity protein binding ATP binding DNA translocase activity methylated histone binding histone binding metal ion binding chromo shadow domain binding	RDH54 (S. cerevisiae)