E2F1 - TTK

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
E2F1	ENSG00000101412	No diseases in record	No drugs in record	core promoter binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein kinase binding sequence-specific DNA binding protein dimerization activity RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II regulatory region DNA binding	E2f1 (D. melanogaster)
TTK	ENSG00000112742	No diseases in record	No drugs in record	protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding protein homodimerization activity RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II distal enhancer sequence-specific DNA binding chromatin binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding POZ domain binding promoter-specific chromatin binding	MPS1 (S. cerevisiae)