TOP2B - NUP98

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2B	ENSG00000077097	No diseases in record	ETOPOSIDE TENIPOSIDE	chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding ATP binding protein C-terminus binding DNA binding, bending enzyme binding histone deacetylase binding metal ion binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
NUP98	ENSG00000110713	AML	No drugs in record	RNA binding transporter activity nucleocytoplasmic transporter activity protein binding nuclear localization sequence binding structural constituent of nuclear pore	NUP145 (S. cerevisiae) npp-10 (C. elegans) Nup98-96 (D. melanogaster)