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PRPF8 - POLE
H. sapiens
SDL interaction
Identifiers
Gene Name
Gene ID
Diseases
Drugs
GO terms
Orthologs
PRPF8
ENSG00000174231
No diseases in record
No drugs in record
second spliceosomal transesterification activity
protein binding
U6 snRNA binding
U1 snRNA binding
U2 snRNA binding
U5 snRNA binding
K63-linked polyubiquitin binding
pre-mRNA intronic binding
PRP8 (S. cerevisiae)
POLE
ENSG00000177084
colorectal carcinoma
endometrioid carcinoma
stomach carcinoma
skin cancer
colorectal cancer susceptibility
CLOFARABINE
CYTARABINE
FLUDARABINE PHOSPHATE
GEMCITABINE
nucleotide binding
DNA binding
chromatin binding
DNA-directed DNA polymerase activity
zinc ion binding
single-stranded DNA 3'-5' exodeoxyribonuclease activity
4 iron, 4 sulfur cluster binding
POL2 (S. cerevisiae)
pole-1 (C. elegans)
DNApol-epsilon255 (D. melanogaster)