PRPF8 - POLE

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PRPF8	ENSG00000174231	No diseases in record	No drugs in record	second spliceosomal transesterification activity protein binding U6 snRNA binding U1 snRNA binding U2 snRNA binding U5 snRNA binding K63-linked polyubiquitin binding pre-mRNA intronic binding	PRP8 (S. cerevisiae)
POLE	ENSG00000177084	colorectal carcinoma endometrioid carcinoma stomach carcinoma skin cancer colorectal cancer susceptibility	CLOFARABINE CYTARABINE FLUDARABINE PHOSPHATE GEMCITABINE	nucleotide binding DNA binding chromatin binding DNA-directed DNA polymerase activity zinc ion binding single-stranded DNA 3'-5' exodeoxyribonuclease activity 4 iron, 4 sulfur cluster binding	POL2 (S. cerevisiae) pole-1 (C. elegans) DNApol-epsilon255 (D. melanogaster)